Apo-CII

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apolipoprotein C-II
Identifiers
Symbol APOC2
Entrez 344
HUGO 609
OMIM 608083
RefSeq NM_000483
UniProt P02655
Other data
Locus Chr. 19 q13.2

Apolipoprotein C2 is an apolipoprotein responsible for the activation of lipoprotein lipase (LPL) in capillaries1 and thus begins the catabolism of the chylomicrons and VLDL. It is also found in HDL. Deficits of this apoprotein C2 present with grave hypertriglyceridemia and hyperchylomicronemia during fasting

References

  1. ^ Kim SY, Park SM, Lee ST (2006). "Apolipoprotein C-II is a novel substrate for matrix metalloproteinases". Biochem. Biophys. Res. Commun. 339 (1): 47–54. doi:10.1016/j.bbrc.2005.10.182. PMID 16314153. 


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  • This page was last modified on 3 December 2008, at 19:07.

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