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Azelnidipine
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| Systematic (IUPAC) name | |
| O3-[1-[di(phenyl)methyl]azetidin-3-yl] O5-propan-2-yl 2-amino-6-methyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate | |
| Identifiers | |
| CAS number | |
| ATC code | ? |
| PubChem | |
| Chemical data | |
| Formula | C33H34N4O6 |
| Mol. mass | 582.64 g/mol |
| SMILES | & |
| Pharmacokinetic data | |
| Bioavailability | ? |
| Metabolism | ? |
| Half life | ? |
| Excretion | ? |
| Therapeutic considerations | |
| Pregnancy cat. |
? |
| Legal status |
℞ Prescription only |
| Routes | Oral |
Azelnidipine (INN; marketed under the brand name Calblock) is a dihydropyridine calcium channel blocker.
Unlike nicardipine, it has a gradual onset and has a long-lasting hypotensive effect, with little increase in heart rate.1
References
- ^ Oizumi K, Nishino H, Koike H, Sada T, Miyamoto M, Kimura T (September 1989). "Antihypertensive effects of CS-905, a novel dihydropyridine Ca++ channel blocker". Jpn. J. Pharmacol. 51 (1): 57–64. PMID 2810942, http://joi.jlc.jst.go.jp/JST.Journalarchive/jphs1951/51.57?from=PubMed.
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Wikipedia content modification information:
- This page was last modified on 5 July 2008, at 11:14.
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