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| Ernest Starling | |
Ernest Starling
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| Born | April 17, 1866 |
|---|---|
| Died | May 2, 1927 |
| Nationality | English |
| Fields | physiology |
| Institutions | University College London |
| Known for | Frank-Starling law of the heart |
Ernest Henry Starling (April 17, 1866 - May 2, 1927) was an English physiologist.1 He worked mainly at University College London, although he also worked for many years in Germany and France. His main collaborator in London was his brother-in-law, Sir William Maddock Bayliss.2
Starling is most famous for developing the "Frank-Starling law of the heart", presented in 1915 and modified in 1919. He is also known for his involvement along with Bayliss in the Brown Dog affair, a controversy relating to vivisection. In 1891, when he was 25, Starling married Florence Amelia Wooldridge, the widow of Leonard Charles Wooldridge, who had been his physiology teacher at Guy's and died at the age of 32. She was a great support to Starling as a sounding board, secretary, and manager of his affairs as well as mother of their four children.
Other major contributions to physiology were:
- The Starling equation, describing fluid shifts in the body (1896)
- The discovery of peristalsis, with Bayliss
- The discovery of secretin, the first hormone, with Bayliss (1902) and the introduction of the concept of hormones (1905)
- The discovery that the distal convoluted tubule of the kidney reabsorbs water and various electrolytes
Starling was elected fellow of the Royal Society in 1899.
Two of his great-grandchildren, Boris Starling (b. 1969) and Belinda Starling (1972-2006) are writers.
References
- ^ Henderson, John (2005). A Life of Ernest Starling. Oxford University Press.
- ^ "Ernest Henry Starling". Whonamedit.com. Retrieved on 2007-11-24.
- Fye, W Bruce (2006), "Ernest Henry Starling.", Clinical cardiology 29 (4): 181–2, 2006 Apr, PMID:16649731, http://www.ncbi.nlm.nih.gov/pubmed/16649731
- Henriksen, Jens H (2005), "Ernest Henry Starling (1866-1927): the scientist and the man.", Journal of medical biography 13 (1): 22–30, 2005 Feb, PMID:15682229, http://www.ncbi.nlm.nih.gov/pubmed/15682229
- Katz, Arnold M (2004), "Ernest Henry Starling: medical educator.", The Pharos of Alpha Omega Alpha-Honor Medical Society. Alpha Omega Alpha 67 (4): 14–21, PMID:15625946, http://www.ncbi.nlm.nih.gov/pubmed/15625946
- Katz, Arnold M (2002), "Ernest Henry Starling, his predecessors, and the "Law of the Heart".", Circulation 106 (23): 2986–92, 2002 Dec 3, PMID:12460884, http://www.ncbi.nlm.nih.gov/pubmed/12460884
- Tucci, P J (1992), "[Ernest Henry Starling--the scientist, the educator, and the fundamental law of the heart", Arq. Bras. Cardiol. 58 (4): 296–302, 1992 Apr, PMID:1340699, http://www.ncbi.nlm.nih.gov/pubmed/1340699
- Fye, W B (1983), "Ernest Henry Starling, his law and its growing significance in the practice of medicine.", Circulation 68 (5): 1145–8, 1983 Nov, PMID:6352082, http://www.ncbi.nlm.nih.gov/pubmed/6352082
- "Ernest Henry Starling (1866-1927).", Triangle; the Sandoz journal of medical science 7 (5): 165, 1966, PMID:5328520, http://www.ncbi.nlm.nih.gov/pubmed/5328520
- BEAN, W B (1963), "Ernest Henry STARLING, the clinican's physiologist, with an aside on wandering navels.", Arch. Intern. Med. 111: 403–5, 1963 Apr, PMID:13969932, http://www.ncbi.nlm.nih.gov/pubmed/13969932
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