This MedLibrary.org supplementary page on Granulosa cell tumour is provided directly from the open source Wikipedia as a service to our readers. Please see the note below on authorship of this content, as well as the Wikipedia usage guidelines. To search for other content from our encyclopedia supplement, please use the form below:
Related Sponsors
| Granulosa cell tumour Classification and external resources |
|
| ICD-10 | C56. |
|---|---|
| ICD-9 | 183 |
| ICD-O: | 8620 |
| eMedicine | med/928 |
| MeSH | D006106 |
 |
This article may require cleanup to meet Wikipedia's quality standards. Please improve this article if you can. (September 2007) |
Granulosa cell tumo(u)rs (or granulosa-theca cell tumo(u)rs) are tumors of the granulosa cell. They are part of the sex cord-stromal tumour group of ovarian neoplasms.
The peak age at which they occur is 50-55 years, but they may occur at any age.
Clinical presentation
Estrogens are produced by functioning tumours, and the clinical presentation depends on the patient's age.
- If the patient is postmenopausal, she usually presents with abnormal uterine bleeding.
- If the patient is of reproductive age, she would present with menometrorrhagia. However, in some cases she may stop ovulating altogether.
- If the patient has not undergone puberty, isosexual-pseudo-precocity may be seen.
Histology
The most characteristic gross appearance is a smooth surfaced solid and cystic lesion with the cysts filled with blood. Hemoperitoneum is an infrequent but classical presentation. A large variety of histological presentations exists, but they have two key features:
- Call-Exner bodies (granulosa cells arranged haphazardly around a space containing eosinophilic fluid); and
- Pale uniform nuclei, often with grooves
There have been cases where the tumor presented as a single, cyst-like, space, with no internal bleeding.
External links
|
||||||||||||||||||||||||||||||||
|
||||||||||||||||||||||||||||||||||||
 |
This oncology article is a stub. You can help Wikipedia by expanding it. |
Wikipedia content modification information:
- This page was last modified on 23 August 2008, at 00:52.
Wikipedia Authorship and Review
Wikipedia content provided here is not reviewed directly by MedLibrary.org. Wikipedia content is authored by an open community of volunteers and is not produced by or in any way affiliated with MedLibrary.org.
Wikipedia Usage Guidelines
This article is licensed under the GNU Free Documentation License. It uses material from the Wikipedia article on "Granulosa cell tumour".
The URL for this specific entry is:
All Wikipedia text is available under the terms of the GNU Free Documentation License. (See Copyrights for details). Wikipedia® is a registered trademark of the Wikimedia Foundation, Inc.