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| Lactose | |
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| IUPAC name | (2S,3R,4R,5S,6R)-6- (hydroxymethyl)-5-((2S,3R,4S,5R,6R)- 3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro- 2H-pyran-2-yloxy)tetrahydro-2H-pyran-2,3,4-triol |
| Other names | Milk Sugar |
| Identifiers | |
| CAS number | [63-42-3] |
| Properties | |
| Molecular formula | C12H22O11 |
| Molar mass | 342.29648 g/mol |
| Appearance | white solid |
| Solubility in water | 0.216 g/mL |
| Except where noted otherwise, data are given for materials in their standard state (at 25 °C, 100 kPa) Infobox references |
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Lactose (also referred to as milk sugar) is a sugar which is found most notably in milk. Lactose makes up around 2–8% of milk (by weight). The name comes from the Latin word for milk, plus the -ose ending used to name sugars. Its systematic name is β-D-galactopyranosyl-(1↔4)β-D-glucopyranose.
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Chemistry
Lactose is a disaccharide that consists of β-D-galactose and β-D-glucose fragments bonded through a β1-4 glycosidic linkage.
Solubility
Lactose has a solubility of 1 in 4.63 measured %w/v. This translates to 0.216 g of lactose dissolving readily in 1 mL of water.
The solubility of lactose in water is 18.9049 g at 25°C, 25.1484 g at 40°C and 37.2149 g at 60°C per 100 g solution. Its solubility in ethanol is 0.0111 g at 40°C and 0.0270 g at 60°C per 100 g solution.[1]
Digestion of lactose
Infant mammals are fed on milk by their mothers. To digest it an enzyme called lactase (β-D-galactosidase) is secreted by the intestinal villi, and this enzyme cleaves the molecule into its two subunits glucose and galactose for absorption.
Since lactose occurs mostly in milk, in most mammals the production of lactase gradually decreases with maturity.
Many people with ancestry in Europe, the Middle East, India, or parts of East Africa, maintain normal lactase production into adulthood. In many of these cultures, mammals such as cattle, goats, and sheep are milked for food. Hence, it was in these regions that genes for lifelong lactase production first evolved. The genes of lactose tolerance have evolved independently in various ethnic groups. [2]
References
- ^ Machado, José J.B.; João A. Coutinho, Eugénia A. Macedo (2000). "Solid–liquid equilibrium of a-lactose in ethanol/water" (PDF). Fluid Phase Equilibria. Retrieved on 2007-12-05.
- ^ People who are not tolerant may suffer certain socially unacceptable symptoms of too much lactose consumption. basically, lactose is not broken down and provides food for gas producing gut flora. This leads to bloating, and flatulence and perhaps GI upset. Nicholas Wade (December 10, 2006). "Study Detects Recent Instance of Human Evolution", The New York Times. Retrieved on 2007-12-05.
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- This page was last modified on 31 August 2008, at 15:51.
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