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Minaprine
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| Systematic (IUPAC) name | |
| 4-methyl-N-(2-morpholin-4-ylethyl)-6-phenylpyridazin-3-amine | |
| Identifiers | |
| CAS number | |
| ATC code | ? |
| PubChem | |
| Chemical data | |
| Formula | C17H22N4O |
| Mol. mass | 298.383 g/mol |
| SMILES | & |
| Pharmacokinetic data | |
| Bioavailability | ? |
| Metabolism | ? |
| Half life | ? |
| Excretion | ? |
| Therapeutic considerations | |
| Pregnancy cat. |
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| Legal status | |
| Routes | ? |
Minaprine is an antidepressant drug which acts as a weak, short-acting monoamine oxidase inhibitor, acting mainly at the MAOA subtype.1 It also has some acetylcholinesterase inhibitory activity.2
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References
- ^ Kan JP, Mouget-Goniot C, Worms P, Biziere K. Effect of the antidepressant minaprine on both forms of monoamine oxidase in the rat. Biochemical Pharmacology. 1986 Mar 15;35(6):973-8. PMID 3954800
- ^ Contreras JM, Rival YM, Chayer S, Bourguignon JJ, Wermuth CG. Aminopyridazines as acetylcholinesterase inhibitors. Journal of Medicinal Chemistry. 1999 Feb 25;42(4):730-41. PMID 10052979
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Wikipedia content modification information:
- This page was last modified on 26 December 2008, at 12:42.
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