Nemonapride

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Nemonapride
Systematic (IUPAC) name
5-Chloro-2-methoxy-4-methylamino-N-[2-methyl-1-(phenylmethyl)pyrrolidin-3-yl]benzamide
Identifiers
CAS number 75272-39-8
ATC code  ?
PubChem 4452
Chemical data
Formula C21H26ClN3O2 
Mol. mass 387.90 g/mol
SMILES eMolecules & PubChem
Pharmacokinetic data
Bioavailability  ?
Metabolism  ?
Half life  ?
Excretion  ?
Therapeutic considerations
Pregnancy cat.

?
Legal status

℞ Prescription only
Routes Oral

Nemonapride (INN, tradename Emilace) is a dopamine receptor antagonist approved in Japan for the treatment of schizophrenia. It also has an effect in methamphetamine sensitization.1

References

  1. ^ Kuribara H, Uchihashi Y (January 1994). "Effects of dopamine antagonism on methamphetamine sensitization: evaluation by ambulatory activity in mice". Pharmacol. Biochem. Behav. 47 (1): 101–6. PMID 8115410, http://linkinghub.elsevier.com/retrieve/pii/0091-3057(94)90117-1. 


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Dopamine antagonists
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Other/unselective
Acepromazine • Alizapride • Amisulpride • Amoxapine • Azaperone • Benperidol • Blonanserin • Bromopride • Butaclamol • Chlorpromazine • Chlorprothixene • Clopenthixol • Domperidone • Droperidol • Eticlopride • Flupentixol • Flupenthixol decanoate • Fluphenazine • Fluspirilene • Haloperidol • Loxapine • Mesoridazine • Methotrimeprazine • Metoclopramide • Mosapramine • Nemonapride • Olanzapine • Penfluridol • Perazine • Perphenazine • Pimozide • Prochlorperazine • Promazine • Promethazine  • Quetiapine • Raclopride • Spiperone • Spiroxatrine • Stepholidine • Sultopride • Tetrahydropalmatine • Thiethylperazine • Thioridazine • Thiothixene • Tiapride • Trifluoperazine • Trifluperidol • Triflupromazine

Wikipedia content modification information:

  • This page was last modified on 28 July 2008, at 02:12.

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