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| Otto Folin | |
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| Born | April 4, 1867 Åsheda, Småland, Sweden |
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| Died | October 23, 1934 (aged 67) |
| Fields | biochemistry |
| Alma mater | University of Minnesota University of Chicago |
| Doctoral advisor | Albrecht Kossel |
| Doctoral students | Edward Adelbert Doisy George H. Hitchings James Batcheller Sumner |
Otto Knut Olof Folin (born April 4, 1867 – October 25, 1934) was a Swedish-born American chemist who is best known for his groundbreaking work on practical micromethods for the determination of the constituents of protein-free blood filtrates and the discovery of creatine phosphate in muscles whilst working at Harvard University.
Folin was born in Åsheda, Småland in Sweden. He moved to America at the age of fifteen following two brothers and an aunt who has already settled there. He carried on his schooling in Stillwater. He moved to Minneapolis, Minnesota and joined the University of Minnesota in 1888. He completed his B.S in 1892. In 1890, he became a citizen of the United States. He joined the University of Chicago in 1892 gaining his Ph.D. in 1898. In 1899 he was appointed assistant professor at West Virginia University. He moved to the McLean Hospital Boston in 1900 as a research biochemist, eventually moving to Harvard Medical School in 1907 as an associate professor of biological chemistry, becoming the Hamilton Kuhn professor in 1909.
Together with Vintilă Ciocâlteu Otto Folin designed the Folin-Ciocalteu reagent to detect polyphenols.
In 1920, he co-developed with Hsien Wu the Folin-Wu method of assaying glucose in protein-free filtrates of blood1.
He died of an heart attack on October 25, 1934
References
- Samuel Meites (1982). "Otto Folin's Decade in Minnesota 1882-1892 A Brief Review". Clinical Chemistry 28 (10): 2173–2177.
- Phillip Schaffer (1954). "Otto Folin: (1867–1934)". Journal of Nutrition 52: 3–11, http://jn.nutrition.org/cgi/reprint/52/1/3.
- Phillip Schaffer (1952). "Otto Folin: (1867–1934)". National Academy Biographical Memoirs 27, http://books.nap.edu/html/biomems/ofolin.pdf.
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